Treatable

Olanzapine

Atypical Antipsychotic

Olanzapine side effects

Adverse Event ReportedReporting Odds RatioCase Count
Diabetes mellitus non-insulin-dependent29.36854603
Metabolic disorder27.94405622
Metabolic disorder27.94405622
Diabetic coma25.39318590
Prescribed overdose22.12254630
Blood cholesterol abnormal20.85158335
Neuroleptic malignant syndrome17.35151865
Diabetic ketoacidosis16.96091929
Diabetes mellitus11.516514406
Obesity10.1726844
Sedation9.40243690
Type 1 diabetes mellitus9.28246320
Blood triglycerides increased8.87354969
Type 2 diabetes mellitus8.360181570
Akathisia7.90663291
Mania7.88233477
Hallucination, auditory7.29302392
Delusion7.19926363
Pancreatitis6.977791598
Muscle rigidity6.92524274
Hospitalisation6.48277466
Hyperglycaemia6.267281224
Diabetic neuropathy6.24845374
Weight increased5.071122957
Blood cholesterol increased4.568491045
Paranoia4.51955298
Intentional overdose4.48706492
Suicide attempt4.46351810
Aggression4.2737739
Overdose4.092441453

Olanzapine desired effects:

  • Decreased Enteric Nervous System GABA Activity
  • Decreased Serotonin Activity
  • Decreased Histamine Activity
  • Decreased Norepinephrine Activity
  • Decreased Dopamine Activity
  • Decreased Acetylcholine Activity

Olanzapine contraindicated conditions:

Olanzapine drug classes:

  • Atypical Antipsychotic

Olanzapine pharmacologic actions:

  • Antiemetics
  • Serotonin Uptake Inhibitors
  • Antipsychotic Agents

Olanzapine mechanism of action:

  • Dopamine Antagonists
  • Adrenergic beta-Antagonists
  • GABA A Antagonists
  • Cholinergic Muscarinic Antagonists
  • Adrenergic alpha-Antagonists
  • Serotonin Antagonists
  • Histamine H1 Receptor Antagonists
  • treatable

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Last updated: 7/24/2021, 4:38:11 AM