Treatable

Clozapine

Atypical Antipsychotic

Clozapine oral suspension

DosageBrandImage
clozapine 50 MG/ML Generic
clozapine 50 MG/ML Versacloz

Clozapine side effects

Adverse Event ReportedReporting Odds RatioCase Count
Differential white blood cell count abnormal133.45918271
Granulocytopenia99.466782154
Antipsychotic drug level increased94.10008650
Neutrophil count increased61.173151644
Myocarditis35.84611450
Salivary hypersecretion29.07002583
Eosinophil count increased18.59809377
White blood cell count increased16.545672147
Neuroleptic malignant syndrome14.51344544
Platelet count increased13.68472464
Agranulocytosis12.85978684
Lower respiratory tract infection12.69963727
Neutrophil count decreased12.046191087
Mental impairment10.81783534
Leukopenia10.625941532
Sedation10.29356560
Hallucination, auditory9.1946365
Delusion8.39152313
C-reactive protein increased7.31397707
Circulatory collapse7.26211423
Hepatitis C7.02381209
White blood cell count decreased6.198511469
Body temperature increased6.14886335
Lymphocyte count decreased6.02849209
Myoclonus5.71582225
Paranoia5.54457270
Electrocardiogram QT prolonged5.39737429
Lung neoplasm malignant5.2747291
Tachycardia5.095971240
Blood creatine phosphokinase increased5.08138613

Clozapine desired effects:

  • Decreased Serotonin Activity
  • Decreased Norepinephrine Activity
  • Decreased Acetylcholine Activity
  • Decreased Dopamine Activity
  • Decreased Histamine Activity

Clozapine drug classes:

  • Atypical Antipsychotic

Clozapine pharmacologic actions:

  • GABA Antagonists
  • Serotonin Antagonists
  • Antipsychotic Agents

Clozapine mechanism of action:

  • Serotonin Antagonists
  • Cholinergic Muscarinic Antagonists
  • Dopamine Antagonists
  • Histamine H1 Receptor Antagonists
  • Adrenergic alpha-Antagonists
  • treatable

Copyright © Treatable 2021
Last updated: 7/16/2021, 4:31:10 AM